Isabel Holguín
- Born: Abt 1582 252
- Marriage: Juan de Vitoria Carvajal Captain
- Died: After 1626, Santa Fé, Santa Fé, Nuevo Méjico, Nueva España 252
 Noted events in her life were:
• Dates & Events. 252
Isabel Holguín, daughter of Juan López Holguín and Catalina de Villaneva was married to Juan de Vitoria Carvajal. She was accused of trafficking in "magic roots" by the church in 1626.
The three known sons were Agustín, Gerónimo and Felis. A daughter of theirs was married to Don Fernando Durán y Cháves. Another likely daughter was Magdalena, wife of Domingo Gonzáles.
~The Origins of New México Families, pg. 14-15
Isabel married Juan de Vitoria Carvajal Captain, son of Juan Carvajal and Unknown. (Juan de Vitoria Carvajal Captain was born in 1561 in Ayotepel, Nueva España 252 and died about 1635 in Nuevo Méjico, Nueva España.)
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